助理教授、副主任医师、硕士生导师
福建省高层人才,厦门市高层次人才
学科方向:内科学,消化病学
研究方向:炎症性肠病,自身免疫性胃炎
单位:皇冠附属第一医院
电子邮箱:hwf0625@xmu.edu.cn
在国家级以上刊物发表论文七十余篇,SCI收录60余篇,多篇发表在医学领域顶刊,总影响因子300余分。2022、2023年度中国消化/肝病科研究最活跃学者。福建省科技厅、厦门市科技局、学术桥专家库评审专家。
研究领域
炎症性肠病基础与临床,自身免疫性胃炎基础与临床,以及消化病学相关疾病的临床研究。
学习经历
2012.9-2015.6,福建医科大学协和临床学院,内科学,博士
2005.9-2008.6,华中科技大学同济皇冠,生理系,硕士
2000.9-2005.7,新乡皇冠临床学院,临床医学,学士
工作经历
2016.10 -至今,皇冠附属第一医院,消化内科
2008.8-2016.10,厦门市医药研究所门诊部/生理室
社会兼职
1.中国抗癌协会肿瘤大数据与真实世界研究专业委员会,青年委员,2019年
2.全国卫生产业企业管理协会精准医疗分会,委员,2019年
3.福建省中西医结合学会代谢与营养分会委员会,常务委员,2020年
4. 福建省医学会消化病学分会委员会青年委员会,委员,2018年
5. 福建省医师协会消化内科医师分会委员会心身疾病学组,副组长,2023年
6. 福建省医学会消化病学委员会炎症性肠病学组,委员,2023年
7. 福建省医学会消化病学委员会肝病学组,委员,2018年
8. 福建省医学会消化病学委员会食管学组,委员,2018年
9. 福建省生理科学会,理事,2019年
10. 福建省海峡医药卫生交流协会临床肿瘤学诊疗分会神经内分泌肿瘤学组,委员,2021年
11. 吴阶平医学基金会炎症性肠病联盟福建省委员会,委员,2018年
12. 厦门市医学会消化内科学分会委员会青年委员会,副主任委员,2022年
13. 厦门市医学会消化病学分会IBD学组,副组长,2022年
14. 厦门市医师协会消化医师分会委员会,委员,2022年
个人获奖
1. 厦门市科技进步奖, 2016
2. 厦门市科技进步奖, 2011
3. 厦门市医学创新奖,2016
4. 厦门市医学创新奖,2015
5. 福建省科技进步奖,2009
研究项目
1. 福建省自然科学基金重点项目,No.2009D026,2009-2012,主持;
2. 福建省卫生厅青年课题,No.2009-2-89,2009-2012,主持;
3. 福建省自然科学基金面上项目,No.2013D009,2013-2016年,主持;
4. 厦门市科技计划项目,No.3502Z20134044,2013-2016,主持;
5. 福建省中医药专项课题,No.wst201202,2013-2016,主持;
6. 福建省医学创新课题,No.2014-CXB-48,2015-2017,主持;
7. 福建省自然科学基金面上项目, No. 2016D017,2016-2019,主持;
8. 厦门市科技计划项目,No. 3502Z20214ZD1028,2021-2024主持;
9. 福建省自然科学基金面上项目,No.2023J011616,2023-2026,主持;
10. 皇冠附属第一医院研究者发起的临床研究基金项目,No.XMFHIIT-2023SL060,2024.01-2026.12,主持;
11. 国家自然科学基金面上项目,No.31272632,2013-2016,骨干;
12. 国家自然科学基金项目面上项目,No.41476119,2015-2018,骨干;
13. 国家自然科学基金项目面上项目,No.81473382,2015-2018,骨干。
代表论文
1. Huang WF, Zheng JW, Chen XQ. Recurrent Abdominal Distension: Colonic Ulcer is a Cause or a Consequence? Gastroenterology. 2022;163(5):e22-e24. 1区IF: 33.883
2. Wu N, Hong SK, Huang WF *. Multiple Strictures of Small Intestine: Is It a Crohn’s Disease? Gastroenterology. 2022;163(5):e1-e2. 1区IF: 33.883
3. Huang WF, Yu J, Zheng JW. An Unusual Case of Gastrointestinal Polyposis. Gastroenterology. 2022;163(3):e1-e3. 1区IF: 33.883
4. Huang WF, Ding Y, Sun J, Zhang JY. More than meets the eye: a strange cause of bowel obstruction and perforation. Gut. 2023 Nov 24;72(12):2259-2320. doi: 10.1136/gutjnl-2023-329568. 1区IF: 31.793
5. Zhang JY, Wu TN, Ding Y, Huang WF*. Unusual cause of abdominal pain. Gut. 2024 Apr 5;73(5):740-824. 1区IF: 31.793
6. Chen YP, Yu J, Huang WF*. An Unusual Cause of Abdominal Pain: Immunoglobulin A Vasculitis. Clin Gastroenterol Hepatol. 2022; 20(7):A17-A18. 1区IF: 13.576
7. Wang SL, Zhang MM, Zhou H, Su GQ, Ding Y, Xu GH, Wang X, Li CF, Huang WF*, Yi LT*. Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation. Biomed J. 2023 Feb 8; S2319-4170(23)00004-5. 1区IF:7.892 (共同通讯)
8. Ye ZW, Yuan ZY, Wang J, Li H, Li CF, Xu GH, Yi LT, Huang WF *. Fucoidan attenuates chronic colitis and behavioral deficits by reshaping gut microbiota-brain axis balance. J Funct Foods. 112 (2024) 105951. 1区,IF:5.6
9. Na Wu, Hua Li, Jinyan Zhang, Weifeng Huang*. Herpes Zoster in a Patient With Ulcerative Colitis After Vedolizumab Initiation-Causal Link or Only Temporal Coincidence? Inflamm Bowel Dis. 2022 Feb 1;28(2):e22-e23. 1区,IF: 7.290
10. Wang X, Tang J, Zheng JW, Huang WF*. Granulomatous Pneumonia and Liver Lesions Associated With Crohn's Disease. Inflamm Bowel Dis. 2022;28(6):e78-e79. 1区,IF: 7.290
11. Lim JY, Yang WL, Huang WF*. An Unusual Endoscopic Appearance of Rectosigmoid Endometriosis. Gastrointest Endosc. 2024 Apr;99(4):656-657. 1区,IF:7.7
12. Gong YQ, Xu Z, Huang WF*. An Unusual Case of Rectal Follicular Lymphoma. Am J Gastroenterol. 2024 Feb 19. doi: 10.14309/ajg.0000000000002662. 1区,IF:10.2
13. Chen LT, Zhang JY, Zheng JW, Yu J, Ding Y, Yang WL, Li H, Huang WF *. The detection rate of granulomas differs between intestinal segments and lesions in Chinese patients with Crohn's disease. Clin Res Hepatol Gastroenterol. 2023 Feb;47(2):102076. 102076. 3区, IF:2.7
14. Wang X, Lu CJ, Li H, Zhang JY, Zheng JW, Wu N, Yang WL, Yu J, Huang WF*. Clinicopathological characteristics of autoimmune gastritis: A single-center retrospective study. Clin Res Hepatol Gastroenterol. 2023 Jun 11;47(7):102154. 3区, IF:2.7
15. Wang X, Ding Y, Li H, Huang WF*. Cap Polyposis. Dig Liver Dis. 2023 Sep;55(9):1295-1296. 2区, IF:4.5
16. Wu N, Su R, Ding Y, Xu Z, Huang WF*. An atypical initial manifestation of IgD myeloma. Am J Med Sci. 2023 Sep 13; S0002-9629(23)01333-2. 2区, IF: 3.1
17. Wu N, Ding Y, Huang W*. A Rare Case of Gastroduodenal Glomus Tumor. Clin Res Hepatol Gastroenterol. 2024 Apr 8:102333. 3区, IF:2.7
18. Wu N, Yu J, Ding Y, Li H, Zhang JY, Huang WF*. An unusual case of diarrhea: Autoimmune enteropathy. Clin Res Hepatol Gastroenterol. 2023 Oct;47(8):102197. 3区, IF:2.7
19. Lim JY, Lu CJ, Huang WF*. An unusual case of diverticulitis protruding into sigmoid colon. Am J Med Sci. 2023 Sep 15; S0002-9629(23)01334-4. 2区, IF: 3.1
20. Zeng XY, Zheng YS, Huang WF*. A gastric hamartomatous inverted polyp mimicking submucosal tumor. Am J Med Sci. 2023 Jun 5; S0002-9629(23)01216-8.2区, IF: 3.1
21. Chen ZC, Yu J, Huang WF*. A solitary gastric juvenile polyp in an older man. Am J Med Sci. 2023 Jun 9; S0002-9629(23)01221-1. 2区, IF: 3.1
22. Wang X, Xu GH, Yu J, Li H, Zhang JY, Huang WF *. When cirrhosis meets paroxysmal nocturnal hemoglobinuria: What kind of "fireworks" scenario will occur? Clin Res Hepatol Gastroenterol. 2023 Jun 22;47(7):102173. 3区, IF:2.7
23. Lu CJ, Zhang JY, Huang WF*. An unusual cause of pneumonia: Strongyloides stercoralis infection. Korean J Intern Med. 2023 Jun 20. 3区,IF:2.4
24. Wang X, Li H, Xu Z, Zhang JY, Huang WF*. An unusual cause of diarrhea: Phlebosclerotic colitis. Am J Med Sci. 2023 Feb 15; S0002-9629(23)01035-2. 2区, IF: 3.462
25. Yan YC, Chen XQ, Yu J, Wang X, Huang WF*. An unusual cause of acute gastrointestinal bleeding: Hookworm infection. Am J Med Sci. 2023 Mar 27; S0002-9629(23)01121-7. 2区, IF: 3.462
26. Wang X, Ding Y, Huang WF*. More than meets the eye: Collision tumors of adenocarcinoma and inflammatory fibroid polyp. Am J Med Sci. 2023 Feb 15; S0002-9629(23)01034-0. 2区, IF: 3.462
27. Lim JY, Hong SK, Huang WF*. Splenic Pseudotumor-Like Follicular Dendritic Cell Sarcoma. J Gastrointest Surg. 2023 Feb 27. 1区, IF: 3.267
28. Tie SJ, Yu J, Huang WF*. An Unusual Case of Gastric Mass: Solitary Gastric Juvenile Polyp. J Gastrointest Surg. 2023 Sep;27(9):2001-2002. 1区, IF: 3.267
29. Wang X, Yu J, Yang WL, Huang WF*. Endoscopic unusual appearance of stomach in a patient with Crohn's disease. Korean J Intern Med. 2023 Mar;38(2):275-276. 3区, IF:3.165
30. Chen LT, Wu JH, Huang WF*. A rare case of gastric adenocarcinoma of fundic gland type. Am J Med Sci. 2023 Sep;366(3):e40-e41. 2区,IF: 3.462
31. Wu N, Hong SK, Huang WF*. Unexpected Cause of Anemia: Primary Small Intestinal Angiosarcoma. J Gastrointest Surg. 2023 Mar;27(3):633-635. 1区,IF: 3.267
32. Gu YB, Sun P, Huang WF*. Heterotopic Gastric Mucosa in the Jejunum and Gastrointestinal Bleeding. J Gastrointest Surg. 2023 Mar;27(3):626-627. 1区,IF: 3.267
33. Zhang Q, Li H, Huang WF*. When Crohn's disease meets IgA nephropathy: What do you think. Am J Med Sci. 2023 May;365(5): e78-e79. 2区,IF: 3.462
34. Huang WF, Zhang JY, Liu W. Gastrointestinal stromal tumor of small intestine. Am J Med Sci. 2022; 364(6): e83-e84. 2区,IF:3.462
35. Ding Y, Hong SK, Huang WF*. More Than Meets the Eye: Abdominopelvic Actinomycosis. J Gastrointest Surg. 2022; 26(10):2241-2243. 1区,IF: 3.267
36. Huang WF, Wang X, Liu W. Primary Malignant Anorectal Melanoma. J Gastrointest Surg. 2022 Jan;26(1):263-265.1区, IF: 3.267
37. Huang WF, Yu J, Liu W. Hereditary Angioedema of the Small Bowel. J Gastrointest Surg. 2022 Jan;26(1):266-267. 1区,IF: 3.267
38. Ding Y, Yu J, Zhang JY, Lu QQ, Wu XR, Huang WF*. An Unusual Colonic Mass in a Phlebosclerosis Patient. Clin Res Hepatol Gastroenterol. 2022;46(4):101865. 3区,IF: 3.189
39. Hong SK, Ding Y, Li H, Zhang JY, Huang WF*. An unusual mass in the colon: Inflammatory myofibroblastic tumor. Clin Res Hepatol Gastroenterol. 2022;46(8):101988. 3区,IF: 3.189
40. Gu YB, Chen XQ, Huang WF*. A Rare Case of Gastrointestinal Polyposis: Cronkhite‑Canada Syndrome. Indian Journal of Surgery. 2022 July 29. 4区,IF: 0.589
41. Zeng XY, Ding Y, Lu QQ, Huang WF*. A Rare Case of Colonic Lymphangioma in an Adult Woman. Indian Journal of Surgery. 2022 June 21. 4区,IF: 0.589
42. Mun R, Wang X, Huang WF*. Gastrocolic fistula, a rare complication of repeated gastric surgery. Korean J Intern Med. 2022; 37(4):877-878. 3区,IF:3.165
43. Huang WF, Zhang JY, Liu W. Multiple Primary Rectal and Gastric Mucosa Lymphoid Lesions-Marginal Zone Non‑Hodgkin B‑Cell Lymphoma. Indian Journal of Surgery. 2022 Jan 3. 4区,IF: 0.589
44. Wang X, Xu Z, Huang WF*. An Amazing Image of Von Hippel-Lindau Syndrome. Indian Journal of Surgery. May 21 2022. 4区,IF: 0.589
45. Huang WF, Liu W. A Case of Exfoliative Esophagitis with Pemphigus Vulgaris. Indian Journal of Surgery. 2021 May 23. 4区,IF: 0.589
46. Huang WF, Zhang JY, Liu W. Blue Rubber Bleb Nevus Syndrome. Indian Journal of Surgery. 2021 Oct 2. 4区,IF: 0.589
47. Wei-Feng Huang, Qi Zhang, Wei Liu. A rare case of aortoduodenal syndrome. Japanese Journal of Gastroenterology Research. May 2022. IF: 1.2
48. Wei-Feng Huang, Yi-Ping Chen, Wei Liu. Metachronous Multiple Clinical Presentations Involving the Skin in a Patient with Immunoglobulin G4–Related Sclerosing Disease. Archives of Medical and Clinical Research. 02 May 2022
49. Xi-Ying Zeng, Xue-Qin Chen, Hua Li, Wei-Feng Huang*. An Unusual Case of Cholestasis and Gastrointestinal Bleeding: Hepatic Cysts. Journal on Surgery. Jul 29, 2022 (2). IF:1.3
50. Wei-Feng Huang, Yi Ding, Wei Liu. Retroperitoneal Castleman’s Disease of the Hyaline-Vascular Type. American Journal of Gastroenterology and Hepatology. 2022. (3)1014
51. Wei-Feng Huang, Yi Ding, Wei Liu. Hyaline vascular-type Castleman’s disease of the retroperitoneum. Arch Clin Gastroenterol 2022. 8(1): 001-002.
52. Ji Li, Wei-Feng Huang, Jin-Yan Zhang. A rare case of duodenal neuroendocrine tumor with hepatic metastasis. Clin Res Hepatol Gastroenterol. 2021 Dec 16;46(3):101850. 3区,IF:2.947
53. Feng Zhang, Hai-Xing Wang, Xu Wang, Wei-Feng Huang*. Pancreatic fistula presenting with bloody ascites and acute peritonitis in a chronic pancreatitis patient: a case report. Journal of Xiangya Medicine. 2021; 6:34
54. Da-Lu Huang, Xu Wang, Wei-Feng Huang*. Ischemic colitis involving the right-side colon: clinical case report and diagnostic considerations. Journal of Xiangya Medicine. 2022.
55. Weifeng Huang, Chunjing Lu, Yong Wu, Shou Ouyang, Yuanzhong Chen. T-type calcium channel antagonists, mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines. J Exp Clin Cancer Res. 34(1):54, 2015.1区,IF: 12.658
56. Weifeng Huang, Chunjing Lu, Yong Wu, Shou Ouyang, Yuanzhong Chen. Identification and functional characterization of voltage-gated sodium channels in lymphocytes. Biochem Biophys Res Commun. 458(2): 294-299, 2015 (SCI收录, IF: 3.575).
57. Wei-Feng Huang, Ming Tang. Role of Sodium Channels in the Spontaneous Excitability of Early Embryonic Cardiomyocytes. Chin J Physiol. 57(4): 188-197, 2014 (SCI收录,IF:1.764)
58. Huang W, Ouyang S, Lu C. Therapy of gastrointestinal pacing for the patients with functional dyspepsia or bathygastria. Neurogastroenterol Motil. 26(S1): 76, 2014 (SCI收录,IF: 4.924)
59. 黄伟锋,卢春敬,许光辉. 汉黄芩素对食管癌KYSE150细胞周期和凋亡的影响. 中医药通报,17(5):63-65,2018
60. 黄伟锋,刘明,栗华,黄玉林,卢春敬. 胃肠起搏器治疗功能性胃肠病的临床疗效分析. 福建医药杂志,39(1):116-118,2017
61. 林冠霞,黄伟锋,史美娜,徐桂华. 溃疡性结肠炎合并巨细胞病毒感染患者临床特点. 中华实验和临床病毒学杂志,32(03):305-308,2018
62. 黄伟锋,欧阳守,卢春敬. 体表胃肠起搏器治疗功能性消化不良的临床研究. 中国中西医结合消化杂志,23(1): 28-30,2015
63. Huang WF, Ouyang S, Li SY, Lin YF, Ouyang H, Zhang H, Lu CJ. Effect of quercetin on colon contractility and L-type Ca2+ channels in colon smooth muscle of guinea-pig. Sheng Li Xue Bao, 61(6):567-76, 2009 (MEDLINE收录)
64. 黄伟锋,欧阳守,张慧. 豚鼠结肠平滑肌细胞大电导钙激活钾通道特性及氧化修饰的影响. 生理学报, 61(3):285-291, 2009 (MEDLINE收录)
65. Yu L, Gao S, Nie L, Tang M, Huang W, Luo H, Hu X, Xi J, Zhu M, Zheng Y, Gao L, Zhang L, Song Y, Hescheler J, Liang H. Molecular and functional changes in voltage-gated Na+ channels in cardiomyocytes during mouse embryogenesis. Circ J. 75(9):2071-9, 2011 (SCI收录)
66. Huang WF, Ouyang S, Lu CJ. The effect of emodin on guinea-pig's colon contractility and a primary study of the effecting mechanism. Neurogastroenterol Motil. 23(S1): 50, 2011 (SCI收录,IF: 4.924)
67. S. OUYANG, Hui ZHANG and Weifeng HUANG. The central mechanism study of microelectrical stimulating and 5-HT microinjection on GEA in the rabbit’s models both of normal and gastric dysrhythmia. Neurogastroenterol Motil. 23(S1): 39, 2011 (SCI收录, IF: 4.924)
68. 黄伟锋,欧阳守. 体表胃肠起搏治疗功能性胃肠道疾病的研究. 实用医学杂志,28(7):1077-1080, 2012
69. 黄伟锋,张慧,欧阳守,卢春敬. 大黄素对兔胃电的影响及其作用机制. 世界华人消化杂志, 20(35):3417-3423, 2012
70. 黄伟锋, 张 慧, 欧阳守, 卢春敬. 5-HT及电刺激对胃节律紊乱模型新西兰白兔胃电活动的影响. 世界华人消化杂志,19(23):2486-2491, 2011
71. 欧阳守,黄伟锋,张慧. 离子通道调整与新药研制——胃肠离子通道病研究最新进展. 临床医学工程, 1:135-139, 2010
72. W. HUANG, S. OUYANG, H. ZHANG and C. LU. Quercetin relax colon smooth muscle of guinea-pig via the interaction of GC and COX stimulation, as well as the antagonism effect on acetylcholine. Neurogastroenterol Motil. 22(S1): 81, 2010
73. Weifeng Huang, Shou Ouyang. The Effects of Nervous Antagonists or Coupling Electrical Gastric Pacing on Phase Difference (PD) of Gastric Electrical Activity (GEA) Peripherally in the Model of Gastric Dysrhythm (GD) Serial. Neuromodulation, 23 AUG:13, 2011
74. 黄伟锋, 欧阳守, 林燕飞, 张 慧. 槲皮素对胃肠运动的影响及其机制. 世界华人消化杂志(CA、EM、AJ收录,核心), 17(18): 1815-1820,2009.